Informations générales
  • Catégorie de maladie Recherche de base (anatomie/physiologie) , Autre (BASEC)
  • Study Phase N/A (ICTRP)
  • État du recrutement recrutement en cours (BASEC/ICTRP)
  • Lieu de l’étude
    Zurich
    (BASEC)
  • Responsable de l'étude Dr. Dario Kohlbrenner dario.kohlbrenner@uzh.ch (BASEC)
  • Source(s) de données BASEC: Importé de 31.03.2025 ICTRP: Importé de 20.03.2025
  • Date de mise à jour 31.03.2025 10:31
HumRes66321 | SNCTP000006261 | BASEC2024-02223 | NCT06856629

The immediate physiological reaction and sensation to eccentric training under blood flow restriction

  • Catégorie de maladie Recherche de base (anatomie/physiologie) , Autre (BASEC)
  • Study Phase N/A (ICTRP)
  • État du recrutement recrutement en cours (BASEC/ICTRP)
  • Lieu de l’étude
    Zurich
    (BASEC)
  • Responsable de l'étude Dr. Dario Kohlbrenner dario.kohlbrenner@uzh.ch (BASEC)
  • Source(s) de données BASEC: Importé de 31.03.2025 ICTRP: Importé de 20.03.2025
  • Date de mise à jour 31.03.2025 10:31

Résumé de l'étude

In this study, we investigate how training under blood flow restriction with eccentric load (i.e., during the braking phase of the movement) affects the physiological systems (e.g., breathing and pulse) of your body and how you perceive the training. To compare the results, you will also perform traditional strength training. Your participation in this study will last a maximum of 2 weeks. We will invite you for 3 study visits. An appointment lasts about 1.5 hours.

(BASEC)

Intervention étudiée

Training under blood flow restriction with eccentric load (i.e., acting only during the braking phase of the movement)

(BASEC)

Maladie en cours d'investigation

Healthy participants

(BASEC)

Critères de participation
Healthy participants aged 18 years and older. (BASEC)

Critères d'exclusion
If you have ever had a thrombosis in your legs or know that you are pregnant, you cannot participate in the study. In the study, you must perform strength training for the legs; if you experience pain during training, you cannot participate. (BASEC)

Lieu de l’étude

Zurich

(BASEC)

Switzerland (ICTRP)

Sponsor

University of Zurich

(BASEC)

Contact pour plus d'informations sur l'étude

Personne de contact en Suisse

Dr. Dario Kohlbrenner

+41 44 634 60 33

dario.kohlbrenner@uzh.ch

Epidemiology, Biostatistics, and Prevention Institute University of Zurich

(BASEC)

Informations générales

+41 44 634 60 33+41 44 634 60 33

dario.kohlbrenner@uzh.ch

(ICTRP)

Nom du comité d'éthique approbateur (pour les études multicentriques, uniquement le comité principal)

Commission cantonale de Zurich

(BASEC)

Date d'approbation du comité d'éthique

31.01.2025

(BASEC)


Identifiant de l'essai ICTRP
NCT06856629 (ICTRP)

Titre officiel (approuvé par le comité d'éthique)
The immediate physiological and perceptual response to blood-flow restricted strength training with eccentric loading (E-BFR): a randomised crossover study in healthy subjects (BASEC)

Titre académique
The Immediate Physiological and Perceptual Response to Blood-flow Restricted Strength Training with Eccentric Loading (E-BFR): a Randomised Crossover Study in Healthy Subjects (ICTRP)

Titre public
The Immediate Physiological and Perceptual Response to Blood-flow Restricted Strength Training with Eccentric Loading (ICTRP)

Maladie en cours d'investigation
Healthy (ICTRP)

Intervention étudiée
Other: Eccentric blood-flow restriction trainingOther: Eccentric free-flow training (ICTRP)

Type d'essai
Interventional (ICTRP)

Plan de l'étude
Allocation: Randomized. Intervention model: Crossover Assignment. Primary purpose: Other. Masking: None (Open Label). (ICTRP)

Critères d'inclusion/exclusion
Inclusion Criteria:

- Clinically Healthy

Exclusion Criteria:

- Physical or intellectual impairment precluding informed consent or protocol
adherence

- Pain during exercise of any origin

- History of thromboembolic event in the lower extremity

- Known pregnancy (no testing is carried out) (ICTRP)

non disponible

Critères d'évaluation principaux et secondaires
minute ventilation (ICTRP)

Other variables from breath-by-breath analysis;Rate of perceived exertion;Near-infrared spectroscopy of the vastus lateralis;Delayed onset muscle soreness;Feasibility and tolerability (ICTRP)

Date d'enregistrement
non disponible

Inclusion du premier participant
non disponible

Sponsors secondaires
non disponible

Contacts supplémentaires
Dario Kohlbrenner, PhDDario Kohlbrenner, PhD, dario.kohlbrenner@uzh.chdario.kohlbrenner@uzh.ch, +41 44 634 60 33+41 44 634 60 33 (ICTRP)

ID secondaires
SNCTP000006261, BASEC2024-02223 (ICTRP)

Résultats-Données individuelles des participants
non disponible

Informations complémentaires sur l'essai
https://clinicaltrials.gov/ct2/show/NCT06856629 (ICTRP)

Résultats de l'essai

Résumé des résultats

non disponible

Lien vers les résultats dans le registre primaire

non disponible