The immediate physiological reaction and sensation to eccentric training under blood flow restriction
Zusammenfassung der Studie
In this study, we investigate how training under blood flow restriction with eccentric load (i.e., during the braking phase of the movement) affects the physiological systems (e.g., breathing and pulse) of your body and how you perceive the training. To compare the results, you will also perform traditional strength training. Your participation in this study will last a maximum of 2 weeks. We will invite you for 3 study visits. An appointment lasts about 1.5 hours.
(BASEC)
Untersuchte Intervention
Training under blood flow restriction with eccentric load (i.e., acting only during the braking phase of the movement)
(BASEC)
Untersuchte Krankheit(en)
Healthy participants
(BASEC)
Healthy participants aged 18 years and older. (BASEC)
Ausschlusskriterien
If you have ever had a thrombosis in your legs or know that you are pregnant, you cannot participate in the study. In the study, you must perform strength training for the legs; if you experience pain during training, you cannot participate. (BASEC)
Studienstandort
Zürich
(BASEC)
Sponsor
University of Zurich
(BASEC)
Kontakt für weitere Auskünfte zur Studie
Kontaktperson Schweiz
Dr. Dario Kohlbrenner
+41 44 634 60 33
dario.kohlbrenner@clutteruzh.chEpidemiology, Biostatistics, and Prevention Institute University of Zurich
(BASEC)
Name der bewilligenden Ethikkommission (bei multizentrischen Studien nur die Leitkommission)
Ethikkommission Zürich
(BASEC)
Datum der Bewilligung durch die Ethikkommission
31.01.2025
(BASEC)
ICTRP Studien-ID
NCT06856629 (ICTRP)
Offizieller Titel (Genehmigt von der Ethikkommission)
The immediate physiological and perceptual response to blood-flow restricted strength training with eccentric loading (E-BFR): a randomised crossover study in healthy subjects (BASEC)
Wissenschaftlicher Titel
The Immediate Physiological and Perceptual Response to Blood-flow Restricted Strength Training with Eccentric Loading (E-BFR): a Randomised Crossover Study in Healthy Subjects (ICTRP)
Öffentlicher Titel
The Immediate Physiological and Perceptual Response to Blood-flow Restricted Strength Training with Eccentric Loading (ICTRP)
Untersuchte Krankheit(en)
Healthy (ICTRP)
Untersuchte Intervention
Other: Eccentric blood-flow restriction trainingOther: Eccentric free-flow training (ICTRP)
Studientyp
Interventional (ICTRP)
Studiendesign
Allocation: Randomized. Intervention model: Crossover Assignment. Primary purpose: Other. Masking: None (Open Label). (ICTRP)
Ein-/Ausschlusskriterien
Inclusion Criteria:
- Clinically Healthy
Exclusion Criteria:
- Physical or intellectual impairment precluding informed consent or protocol
adherence
- Pain during exercise of any origin
- History of thromboembolic event in the lower extremity
- Known pregnancy (no testing is carried out) (ICTRP)
nicht verfügbar
Primäre und sekundäre Endpunkte
minute ventilation (ICTRP)
Other variables from breath-by-breath analysis;Rate of perceived exertion;Near-infrared spectroscopy of the vastus lateralis;Delayed onset muscle soreness;Feasibility and tolerability (ICTRP)
Registrierungsdatum
nicht verfügbar
Einschluss des ersten Teilnehmers
nicht verfügbar
Sekundäre Sponsoren
nicht verfügbar
Weitere Kontakte
Dario Kohlbrenner, PhDDario Kohlbrenner, PhD, dario.kohlbrenner@uzh.chdario.kohlbrenner@uzh.ch, +41 44 634 60 33+41 44 634 60 33 (ICTRP)
Sekundäre IDs
SNCTP000006261, BASEC2024-02223 (ICTRP)
Angaben zur Verfügbarkeit von individuellen Teilnehmerdaten
nicht verfügbar
Weitere Informationen zur Studie
https://clinicaltrials.gov/ct2/show/NCT06856629 (ICTRP)
Ergebnisse der Studie
Zusammenfassung der Ergebnisse
nicht verfügbar
Link zu den Ergebnissen im Primärregister
nicht verfügbar