Informazioni generali
  • Categoria della malattia Ricerca fondamentale (anatomia / fisiologia) , Altro (BASEC)
  • Fase dello studio N/A (ICTRP)
  • Stato di reclutamento reclutamento in corso (BASEC/ICTRP)
  • Luogo dello studio
    Zurigo
    (BASEC)
  • Responsabile dello studio Dr. Dario Kohlbrenner dario.kohlbrenner@uzh.ch (BASEC)
  • Fonte dati BASEC: Importato da 31.03.2025 ICTRP: Importato da 20.03.2025
  • Ultimo aggiornamento 31.03.2025 10:31
HumRes66321 | SNCTP000006261 | BASEC2024-02223 | NCT06856629

The immediate physiological reaction and sensation to eccentric training under blood flow restriction

  • Categoria della malattia Ricerca fondamentale (anatomia / fisiologia) , Altro (BASEC)
  • Fase dello studio N/A (ICTRP)
  • Stato di reclutamento reclutamento in corso (BASEC/ICTRP)
  • Luogo dello studio
    Zurigo
    (BASEC)
  • Responsabile dello studio Dr. Dario Kohlbrenner dario.kohlbrenner@uzh.ch (BASEC)
  • Fonte dati BASEC: Importato da 31.03.2025 ICTRP: Importato da 20.03.2025
  • Ultimo aggiornamento 31.03.2025 10:31

Descrizione riassuntiva dello studio

In this study, we investigate how training under blood flow restriction with eccentric load (i.e., during the braking phase of the movement) affects the physiological systems (e.g., breathing and pulse) of your body and how you perceive the training. To compare the results, you will also perform traditional strength training. Your participation in this study will last a maximum of 2 weeks. We will invite you for 3 study visits. An appointment lasts about 1.5 hours.

(BASEC)

Intervento studiato

Training under blood flow restriction with eccentric load (i.e., acting only during the braking phase of the movement)

(BASEC)

Malattie studiate

Healthy participants

(BASEC)

Criteri di partecipazione
Healthy participants aged 18 years and older. (BASEC)

Criteri di esclusione
If you have ever had a thrombosis in your legs or know that you are pregnant, you cannot participate in the study. In the study, you must perform strength training for the legs; if you experience pain during training, you cannot participate. (BASEC)

Luogo dello studio

Zurigo

(BASEC)

Switzerland (ICTRP)

Sponsor

University of Zurich

(BASEC)

Contatto per ulteriori informazioni sullo studio

Persona di contatto in Svizzera

Dr. Dario Kohlbrenner

+41 44 634 60 33

dario.kohlbrenner@uzh.ch

Epidemiology, Biostatistics, and Prevention Institute University of Zurich

(BASEC)

Informazioni generali

+41 44 634 60 33+41 44 634 60 33

dario.kohlbrenner@uzh.ch

(ICTRP)

Nome del comitato etico approvante (per studi multicentrici solo il comitato principale)

Commissione etica Zurigo

(BASEC)

Data di approvazione del comitato etico

31.01.2025

(BASEC)


ID di studio ICTRP
NCT06856629 (ICTRP)

Titolo ufficiale (approvato dal comitato etico)
The immediate physiological and perceptual response to blood-flow restricted strength training with eccentric loading (E-BFR): a randomised crossover study in healthy subjects (BASEC)

Titolo accademico
The Immediate Physiological and Perceptual Response to Blood-flow Restricted Strength Training with Eccentric Loading (E-BFR): a Randomised Crossover Study in Healthy Subjects (ICTRP)

Titolo pubblico
The Immediate Physiological and Perceptual Response to Blood-flow Restricted Strength Training with Eccentric Loading (ICTRP)

Malattie studiate
Healthy (ICTRP)

Intervento studiato
Other: Eccentric blood-flow restriction trainingOther: Eccentric free-flow training (ICTRP)

Tipo di studio
Interventional (ICTRP)

Disegno dello studio
Allocation: Randomized. Intervention model: Crossover Assignment. Primary purpose: Other. Masking: None (Open Label). (ICTRP)

Criteri di inclusione/esclusione
Inclusion Criteria:

- Clinically Healthy

Exclusion Criteria:

- Physical or intellectual impairment precluding informed consent or protocol
adherence

- Pain during exercise of any origin

- History of thromboembolic event in the lower extremity

- Known pregnancy (no testing is carried out) (ICTRP)

non disponibile

Endpoint primari e secondari
minute ventilation (ICTRP)

Other variables from breath-by-breath analysis;Rate of perceived exertion;Near-infrared spectroscopy of the vastus lateralis;Delayed onset muscle soreness;Feasibility and tolerability (ICTRP)

Data di registrazione
non disponibile

Inclusione del primo partecipante
non disponibile

Sponsor secondari
non disponibile

Contatti aggiuntivi
Dario Kohlbrenner, PhDDario Kohlbrenner, PhD, dario.kohlbrenner@uzh.chdario.kohlbrenner@uzh.ch, +41 44 634 60 33+41 44 634 60 33 (ICTRP)

ID secondari
SNCTP000006261, BASEC2024-02223 (ICTRP)

Risultati-Dati individuali dei partecipanti
non disponibile

Ulteriori informazioni sullo studio
https://clinicaltrials.gov/ct2/show/NCT06856629 (ICTRP)

Risultati dello studio

Riepilogo dei risultati

non disponibile

Link ai risultati nel registro primario

non disponibile