Comparison of prostate cancer screening between a standardized 3T MRI protocol and low field MRI: A prospective study.
Résumé de l'étude
This study aims to compare the effectiveness of low field MRI (0.55T) with traditional high field MRI (3T) in screening for prostate cancer and improving image quality. It is conducted in three phases: first, a pilot study with healthy volunteers to optimize the low field MRI protocol; then, an assessment of image quality between the two types of MRI in patients with metallic artifacts, particularly due to hip prostheses; finally, the evaluation of low field MRI in patients with suspicious prostate lesions on high field MRI (3T). Additionally, we will look back to study patients who underwent surgery for prostate cancer between 2018 and 2024. We will examine and measure the quality of prostate images taken no later than 6 months prior to surgery. We will also study the shape of the prostate in 3D and extract data from the images to better understand cancer. Our goal is to find an accessible solution for prostate cancer screening while maintaining or improving image quality.
(BASEC)
Intervention étudiée
MRI screening for prostate cancer.
(BASEC)
Maladie en cours d'investigation
Prostate cancer
(BASEC)
Phase 2: Study of 0.55T MRI of the prostate in adult men with metallic implants. We include those whose 3T MRIs are deemed insufficient due to these implants. Phase 3: Evaluation of 0.55T MRI of the prostate in adult men with suspicious lesions. We include those whose 3T MRIs detected lesions classified as PI-RADS 4/5 and who are scheduled for targeted prostate biopsy. Phase 4: Comparison of imaging quality and radiomic data with a retrospective cohort. We include adult men who had prostate cancer and radical prostatectomy, and who underwent 3T MRI of the prostate prior to surgery. (BASEC)
Critères d'exclusion
Phase 2 and 3: - Any condition making the patient unsuitable for the study (contraindication to MRI). - Refusal to be informed in case of incidental findings on MRI. Phase 3: History of prostate cancer. Phase 4: Patients who underwent diagnostic 3T MRI of the prostate more than 6 months prior to surgery and 1.5T MRI of the prostate. (BASEC)
Lieu de l’étude
Lausanne
(BASEC)
Sponsor
Prof. Ileana Jelescu
(BASEC)
Contact pour plus d'informations sur l'étude
Personne de contact en Suisse
NaïK Vietti Violi
+41795560240
naik.vietti-violi@clutterchuv.chLausanne university hospital
(BASEC)
Informations scientifiques
non disponible
Nom du comité d'éthique approbateur (pour les études multicentriques, uniquement le comité principal)
Commission cantonale d'éthique du Vaud
(BASEC)
Date d'approbation du comité d'éthique
27.06.2024
(BASEC)
Identifiant de l'essai ICTRP
non disponible
Titre officiel (approuvé par le comité d'éthique)
Comparing prostate cancer screening between standardized 3T MRI screening protocol and Low-Field MRI in a prospective study (BASEC)
Titre académique
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Titre public
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Maladie en cours d'investigation
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Intervention étudiée
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Type d'essai
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Plan de l'étude
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Critères d'inclusion/exclusion
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non disponible
Critères d'évaluation principaux et secondaires
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Date d'enregistrement
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Inclusion du premier participant
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Sponsors secondaires
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Contacts supplémentaires
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ID secondaires
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Résultats-Données individuelles des participants
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Informations complémentaires sur l'essai
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Résultats de l'essai
Résumé des résultats
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Lien vers les résultats dans le registre primaire
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