Comparison of prostate cancer screening between a standardized 3T MRI protocol and low field MRI: A prospective study.
Descrizione riassuntiva dello studio
This study aims to compare the effectiveness of low field MRI (0.55T) with traditional high field MRI (3T) in screening for prostate cancer and improving image quality. It is conducted in three phases: first, a pilot study with healthy volunteers to optimize the low field MRI protocol; then, an assessment of image quality between the two types of MRI in patients with metallic artifacts, particularly due to hip prostheses; finally, the evaluation of low field MRI in patients with suspicious prostate lesions on high field MRI (3T). Additionally, we will look back to study patients who underwent surgery for prostate cancer between 2018 and 2024. We will examine and measure the quality of prostate images taken no later than 6 months prior to surgery. We will also study the shape of the prostate in 3D and extract data from the images to better understand cancer. Our goal is to find an accessible solution for prostate cancer screening while maintaining or improving image quality.
(BASEC)
Intervento studiato
MRI screening for prostate cancer.
(BASEC)
Malattie studiate
Prostate cancer
(BASEC)
Phase 2: Study of 0.55T MRI of the prostate in adult men with metallic implants. We include those whose 3T MRIs are deemed insufficient due to these implants. Phase 3: Evaluation of 0.55T MRI of the prostate in adult men with suspicious lesions. We include those whose 3T MRIs detected lesions classified as PI-RADS 4/5 and who are scheduled for targeted prostate biopsy. Phase 4: Comparison of imaging quality and radiomic data with a retrospective cohort. We include adult men who had prostate cancer and radical prostatectomy, and who underwent 3T MRI of the prostate prior to surgery. (BASEC)
Criteri di esclusione
Phase 2 and 3: - Any condition making the patient unsuitable for the study (contraindication to MRI). - Refusal to be informed in case of incidental findings on MRI. Phase 3: History of prostate cancer. Phase 4: Patients who underwent diagnostic 3T MRI of the prostate more than 6 months prior to surgery and 1.5T MRI of the prostate. (BASEC)
Luogo dello studio
Losanna
(BASEC)
Sponsor
Prof. Ileana Jelescu
(BASEC)
Contatto per ulteriori informazioni sullo studio
Persona di contatto in Svizzera
NaïK Vietti Violi
+41795560240
naik.vietti-violi@clutterchuv.chLausanne university hospital
(BASEC)
Informazioni scientifiche
non disponibile
Nome del comitato etico approvante (per studi multicentrici solo il comitato principale)
Commissione d'etica Vaud
(BASEC)
Data di approvazione del comitato etico
27.06.2024
(BASEC)
ID di studio ICTRP
non disponibile
Titolo ufficiale (approvato dal comitato etico)
Comparing prostate cancer screening between standardized 3T MRI screening protocol and Low-Field MRI in a prospective study (BASEC)
Titolo accademico
non disponibile
Titolo pubblico
non disponibile
Malattie studiate
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Intervento studiato
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Tipo di studio
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Disegno dello studio
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Criteri di inclusione/esclusione
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non disponibile
Endpoint primari e secondari
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non disponibile
Data di registrazione
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Inclusione del primo partecipante
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Sponsor secondari
non disponibile
Contatti aggiuntivi
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ID secondari
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Risultati-Dati individuali dei partecipanti
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Ulteriori informazioni sullo studio
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Risultati dello studio
Riepilogo dei risultati
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Link ai risultati nel registro primario
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