Plasma Oxytocin Changes in Response to Music Modified by Sound Amplification Technology Compared to Non-modified Control Music in Healthy Controls and Patients with AVP Deficiency
Résumé de l'étude
The aim of this scientific study is to investigate the concentration of oxytocin using music modified by sound amplification technology in healthy participants. Small previous studies have demonstrated oxytocin release in healthy individuals with this modified music. We now want to investigate whether this is reproducible.
Oxytocin is a hormone produced in the brain and released into the bloodstream by the pituitary gland. It is involved in important psychosocial aspects and has a positive influence on the mother-child relationship, as well as feelings such as love, trust, and relaxation. In some conditions, such as in patients with pituitary gland disorders, a reduced concentration of oxytocin in the blood is suspected. This could explain why patients often experience symptoms such as anxiety and depression. Music modified by sound amplification technology is a new technology that is taking its first steps in medicine. Currently, sound amplification technology is not approved as a medical intervention but has been used in various studies with healthy subjects. Some studies have shown that this modified music leads to an increase in oxytocin in healthy participants.
(BASEC)
Intervention étudiée
Music modified with sound amplification technology
(BASEC)
Maladie en cours d'investigation
AVP deficiency or oxytocin deficiency
(BASEC)
You are between 18 and 65 years old
Healthy and not taking any medications (except hormonal contraception)
(BASEC)
Critères d'exclusion
Pregnant or breastfeeding
Have ever suffered from a psychotic disorder (e.g., schizophrenia, bipolar disorder)
Currently being treated for a severe psychiatric disorder (e.g., severe depression)
(BASEC)
Lieu de l’étude
Bâle
(BASEC)
Sponsor
Mirjam Christ-Crain
(BASEC)
Contact pour plus d'informations sur l'étude
Personne de contact en Suisse
Andi Nikaj
0041 61 328 57 43
andi.nikaj@clutterusb.chUniversity Hospital Basel
(BASEC)
Informations scientifiques
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Nom du comité d'éthique approbateur (pour les études multicentriques, uniquement le comité principal)
Ethikkommission Nordwest- und Zentralschweiz EKNZ
(BASEC)
Date d'approbation du comité d'éthique
25.11.2025
(BASEC)
Identifiant de l'essai ICTRP
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Titre officiel (approuvé par le comité d'éthique)
Plasma Oxytocin Changes in Response to Music Modified by Sonic Augmentation Technology vs Unaugmented Control Music in Healthy Controls and Patients with AVP-Deficiency – The TechnOXY Study (BASEC)
Titre académique
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Titre public
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Maladie en cours d'investigation
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Intervention étudiée
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Type d'essai
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Plan de l'étude
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Critères d'inclusion/exclusion
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Critères d'évaluation principaux et secondaires
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Date d'enregistrement
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Inclusion du premier participant
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Sponsors secondaires
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Contacts supplémentaires
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ID secondaires
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Résultats-Données individuelles des participants
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Informations complémentaires sur l'essai
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Résultats de l'essai
Résumé des résultats
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Lien vers les résultats dans le registre primaire
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