General information
  • Disease category Endocrinological diseases (non cancer) (BASEC)
  • Recruitment status recruitment ongoing (BASEC/ICTRP)
  • Trial sites
    Basel
    (BASEC)
  • Contact Andi Nikaj andi.nikaj@usb.ch (BASEC)
  • Data Source(s) BASEC: Import from 14.01.2026 ICTRP: N/A
  • Last update 14.01.2026 10:35
HumRes67545 | SNCTP000006685 | BASEC2025-01817

Plasma Oxytocin Changes in Response to Music Modified by Sound Amplification Technology Compared to Non-modified Control Music in Healthy Controls and Patients with AVP Deficiency

  • Disease category Endocrinological diseases (non cancer) (BASEC)
  • Recruitment status recruitment ongoing (BASEC/ICTRP)
  • Trial sites
    Basel
    (BASEC)
  • Contact Andi Nikaj andi.nikaj@usb.ch (BASEC)
  • Data Source(s) BASEC: Import from 14.01.2026 ICTRP: N/A
  • Last update 14.01.2026 10:35

Summary description of the study

The aim of this scientific study is to investigate the concentration of oxytocin using music modified by sound amplification technology in healthy participants. Small previous studies have demonstrated oxytocin release in healthy individuals with this modified music. We now want to investigate whether this is reproducible.

Oxytocin is a hormone produced in the brain and released into the bloodstream by the pituitary gland. It is involved in important psychosocial aspects and has a positive influence on the mother-child relationship, as well as feelings such as love, trust, and relaxation. In some conditions, such as in patients with pituitary gland disorders, a reduced concentration of oxytocin in the blood is suspected. This could explain why patients often experience symptoms such as anxiety and depression. Music modified by sound amplification technology is a new technology that is taking its first steps in medicine. Currently, sound amplification technology is not approved as a medical intervention but has been used in various studies with healthy subjects. Some studies have shown that this modified music leads to an increase in oxytocin in healthy participants.

(BASEC)

Intervention under investigation

Music modified with sound amplification technology

(BASEC)

Disease under investigation

AVP deficiency or oxytocin deficiency

(BASEC)

Criteria for participation in trial

You are between 18 and 65 years old
Healthy and not taking any medications (except hormonal contraception)

(BASEC)


Exclusion criteria

Pregnant or breastfeeding
Have ever suffered from a psychotic disorder (e.g., schizophrenia, bipolar disorder)
Currently being treated for a severe psychiatric disorder (e.g., severe depression)

(BASEC)

Trial sites

Basel

(BASEC)

not available

Sponsor

Mirjam Christ-Crain

(BASEC)

Contact

Contact Person Switzerland

Andi Nikaj

0041 61 328 57 43

andi.nikaj@usb.ch

University Hospital Basel

(BASEC)

Scientific Information

not available

Name of the authorising ethics committee (for multicentre studies, only the lead committee)

Ethics Committee northwest/central Switzerland EKNZ

(BASEC)

Date of authorisation

25.11.2025

(BASEC)


ICTRP Trial ID
not available

Official title (approved by ethics committee)
Plasma Oxytocin Changes in Response to Music Modified by Sonic Augmentation Technology vs Unaugmented Control Music in Healthy Controls and Patients with AVP-Deficiency – The TechnOXY Study (BASEC)

Academic title
not available

Public title
not available

Disease under investigation
not available

Intervention under investigation
not available

Type of trial
not available

Trial design
not available

Inclusion/Exclusion criteria
not available

not available

Primary and secondary end points
not available

not available

Registration date
not available

Incorporation of the first participant
not available

Secondary sponsors
not available

Additional contacts
not available

Secondary trial IDs
not available

Results-Individual Participant Data (IPD)
not available

Further information on the trial
not available

Results of the trial

Results summary

not available

Link to the results in the primary register

not available