Investigation of Fatigue Using Digital Technologies

The aim of this exploratory study is to assess the feasibility of long-term fatigue monitoring based on compliance rates for the use of wearable devices and the completion of app tasks. This assessment will show whether the approach has the potential for future monitoring of MS and Long-COVID patients.

Your participation is required for two months and includes two clinic visits and a data collection phase:

• Preparation at home: You will receive the consent form for the study (this document) and the user manuals.
• First study visit: You will sign the consent form together with the study team. You will undergo a medical examination, fill out questionnaires, and become familiar with the digital technologies of the study. The study visit lasts about two hours.
• Data collection phase: You will continuously wear two wearable devices for two months (24/7), charge them regularly, and download the data. Additionally, you will use the FIDO app to perform short tasks (about 7 minutes every two days) and fill out short questionnaires at regular intervals (~5 minutes per day). The app is intuitive and self-explanatory and will send you notifications to remind you of the tasks. Additionally, after 4 and 8 weeks, you should collect a stool sample at home for an analysis of your gut bacteria and fill out two questionnaires.
• Last study visit: After the two months, you will visit the clinic again for a second medical examination and provide feedback on the digital technology. You will also return the devices. The study visit lasts 60 to 90 minutes.

Fatigue in Healthy Individuals and MS & Long COVID Patients