Use of hypnosis to improve patient well-being after intensive care hospitalization and prevent post-intensive care syndrome
Résumé de l'étude
This study aims to investigate the effect of hypnosis to help patients after a stay in intensive care. A first hypnosis session is offered at the time of discharge from the intensive care unit, followed by two more sessions on days 7 and 14. We believe that this can improve the short-term well-being of these patients and reduce, in the longer term, the symptoms of post-intensive care syndrome that affect 20-40% of patients 3 to 6 months after an intensive care stay, manifesting as anxiety, sadness, and a decrease in quality of life.
(BASEC)
Intervention étudiée
Preventive hypnosis session on the day of discharge from intensive care, then on day 7 +/- day 14
(BASEC)
Maladie en cours d'investigation
Post-intensive care syndrome
(BASEC)
All patients admitted to intensive care meeting the following criteria: • Aged ≥18 years • Under mechanical ventilation for at least 48 hours • Able to give informed consent, documented by a signature • French-speaking (BASEC)
Critères d'exclusion
Exclusion criteria: • Patient refusal • Patient transferred from another intensive care unit • Patient at the end of life or for whom withdrawal of care is planned • Glasgow Coma Scale (GCS) <15 at discharge from intensive care • Presence of delirium at discharge from intensive care (detected by CAM-ICU) • Prior cognitive impairment • Intensive care hospitalization for a brain injury • Incarcerated patient • Intensive care hospitalization for more than 28 days (BASEC)
Lieu de l’étude
Genève, Neuchâtel
(BASEC)
Sponsor
Matteo Coen
(BASEC)
Contact pour plus d'informations sur l'étude
Personne de contact en Suisse
Matteo Coen and Hannah Wozniak
079 55 30 291
Matteo.coen@clutterhug.chHUG
(BASEC)
Informations générales
University Hospital, GenevaUniversity Hospital, Geneva
+41
hannah-wozniak@hug.ch(ICTRP)
Nom du comité d'éthique approbateur (pour les études multicentriques, uniquement le comité principal)
Commission cantonale d'éthique de Genève
(BASEC)
Date d'approbation du comité d'éthique
11.03.2026
(BASEC)
Identifiant de l'essai ICTRP
NCT07254299 (ICTRP)
Titre officiel (approuvé par le comité d'éthique)
Hypnosis to Improve Well-beings of Critically Ill Patients and Prevent Post-intensive Care Syndrome (HypnoPICS) (BASEC)
Titre académique
Hypnosis to Improve Well-beings of Critically Ill Patients and Prevent Post-intensive Care Syndrome (ICTRP)
Titre public
Hypnosis to Improve Well-beings of Critically Ill Patients and Prevent Post-intensive Care Syndrome (ICTRP)
Maladie en cours d'investigation
Post Intensive Care Syndrome (PICS) (ICTRP)
Intervention étudiée
Other: Hypnosis (ICTRP)
Type d'essai
Interventional (ICTRP)
Plan de l'étude
Allocation: Randomized. Intervention model: Parallel Assignment. Primary purpose: Prevention. Masking: Single (Outcomes Assessor). (ICTRP)
Critères d'inclusion/exclusion
Inclusion Criteria:
- On Mechanical Ventilation for at least 2 days
- Able to give informed consent as documented by signature
- French speaking
Exclusion Criteria:
- Refusal of the patient
- Patient transferred from another ICU
- Patient is planned for a withdrawal of care or is actively dying
- Glasgow coma scale (GCS) <15 on ICU discharge
- Patient presenting with delirium (detected by CAM-ICU) on ICU discharge
- Patient hospitalized for traumatic brain injury
- Patient is in jail
- Patient hospitalized for more than 28 days in the ICU (ICTRP)
non disponible
Critères d'évaluation principaux et secondaires
Wellbeing at day 28 post intensive care unit discharge (ICTRP)
Immediate wellbeing following a hypnosis session;PDI - Peritraumatic distress inventory;PHQ-9 - Patient Health Questionnaire-9;GAD-7 - Generalized Anxiety Disorder-7;IES-R (Impact of event Scale);EQ-5D-5L (Quality of life);PGIC - Patient Global Impression of Change (ICTRP)
Date d'enregistrement
14.11.2025 (ICTRP)
Inclusion du premier participant
non disponible
Sponsors secondaires
non disponible
Contacts supplémentaires
Hannah Wozniak, Medical DoctorMatteo Coen, MD, PHDHannah Wozniak, Medical Doctor, hannah-wozniak@hug.ch, +41, University Hospital, GenevaUniversity Hospital, Geneva (ICTRP)
ID secondaires
2025-00369 (ICTRP)
Résultats-Données individuelles des participants
non disponible
Informations complémentaires sur l'essai
https://clinicaltrials.gov/study/NCT07254299 (ICTRP)
Résultats de l'essai
Résumé des résultats
non disponible
Lien vers les résultats dans le registre primaire
non disponible