Use of hypnosis to improve patient well-being after intensive care hospitalization and prevent post-intensive care syndrome
Zusammenfassung der Studie
This study aims to investigate the effect of hypnosis to help patients after a stay in intensive care. A first hypnosis session is offered at the time of discharge from the intensive care unit, followed by two more sessions on days 7 and 14. We believe that this can improve the short-term well-being of these patients and reduce, in the longer term, the symptoms of post-intensive care syndrome that affect 20-40% of patients 3 to 6 months after an intensive care stay, manifesting as anxiety, sadness, and a decrease in quality of life.
(BASEC)
Untersuchte Intervention
Preventive hypnosis session on the day of discharge from intensive care, then on day 7 +/- day 14
(BASEC)
Untersuchte Krankheit(en)
Post-intensive care syndrome
(BASEC)
All patients admitted to intensive care meeting the following criteria: • Aged ≥18 years • Under mechanical ventilation for at least 48 hours • Able to give informed consent, documented by a signature • French-speaking (BASEC)
Ausschlusskriterien
Exclusion criteria: • Patient refusal • Patient transferred from another intensive care unit • Patient at the end of life or for whom withdrawal of care is planned • Glasgow Coma Scale (GCS) <15 at discharge from intensive care • Presence of delirium at discharge from intensive care (detected by CAM-ICU) • Prior cognitive impairment • Intensive care hospitalization for a brain injury • Incarcerated patient • Intensive care hospitalization for more than 28 days (BASEC)
Studienstandort
Genf, Neuenburg
(BASEC)
Sponsor
Matteo Coen
(BASEC)
Kontakt für weitere Auskünfte zur Studie
Kontaktperson Schweiz
Matteo Coen and Hannah Wozniak
079 55 30 291
Matteo.coen@clutterhug.chHUG
(BASEC)
Allgemeine Auskünfte
University Hospital, GenevaUniversity Hospital, Geneva
+41
hannah-wozniak@hug.ch(ICTRP)
Name der bewilligenden Ethikkommission (bei multizentrischen Studien nur die Leitkommission)
Ethikkommission Genf
(BASEC)
Datum der Bewilligung durch die Ethikkommission
11.03.2026
(BASEC)
ICTRP Studien-ID
NCT07254299 (ICTRP)
Offizieller Titel (Genehmigt von der Ethikkommission)
Hypnosis to Improve Well-beings of Critically Ill Patients and Prevent Post-intensive Care Syndrome (HypnoPICS) (BASEC)
Wissenschaftlicher Titel
Hypnosis to Improve Well-beings of Critically Ill Patients and Prevent Post-intensive Care Syndrome (ICTRP)
Öffentlicher Titel
Hypnosis to Improve Well-beings of Critically Ill Patients and Prevent Post-intensive Care Syndrome (ICTRP)
Untersuchte Krankheit(en)
Post Intensive Care Syndrome (PICS) (ICTRP)
Untersuchte Intervention
Other: Hypnosis (ICTRP)
Studientyp
Interventional (ICTRP)
Studiendesign
Allocation: Randomized. Intervention model: Parallel Assignment. Primary purpose: Prevention. Masking: Single (Outcomes Assessor). (ICTRP)
Ein-/Ausschlusskriterien
Inclusion Criteria:
- On Mechanical Ventilation for at least 2 days
- Able to give informed consent as documented by signature
- French speaking
Exclusion Criteria:
- Refusal of the patient
- Patient transferred from another ICU
- Patient is planned for a withdrawal of care or is actively dying
- Glasgow coma scale (GCS) <15 on ICU discharge
- Patient presenting with delirium (detected by CAM-ICU) on ICU discharge
- Patient hospitalized for traumatic brain injury
- Patient is in jail
- Patient hospitalized for more than 28 days in the ICU (ICTRP)
nicht verfügbar
Primäre und sekundäre Endpunkte
Wellbeing at day 28 post intensive care unit discharge (ICTRP)
Immediate wellbeing following a hypnosis session;PDI - Peritraumatic distress inventory;PHQ-9 - Patient Health Questionnaire-9;GAD-7 - Generalized Anxiety Disorder-7;IES-R (Impact of event Scale);EQ-5D-5L (Quality of life);PGIC - Patient Global Impression of Change (ICTRP)
Registrierungsdatum
14.11.2025 (ICTRP)
Einschluss des ersten Teilnehmers
nicht verfügbar
Sekundäre Sponsoren
nicht verfügbar
Weitere Kontakte
Hannah Wozniak, Medical DoctorMatteo Coen, MD, PHDHannah Wozniak, Medical Doctor, hannah-wozniak@hug.ch, +41, University Hospital, GenevaUniversity Hospital, Geneva (ICTRP)
Sekundäre IDs
2025-00369 (ICTRP)
Angaben zur Verfügbarkeit von individuellen Teilnehmerdaten
nicht verfügbar
Weitere Informationen zur Studie
https://clinicaltrials.gov/study/NCT07254299 (ICTRP)
Ergebnisse der Studie
Zusammenfassung der Ergebnisse
nicht verfügbar
Link zu den Ergebnissen im Primärregister
nicht verfügbar