Informations générales
  • Catégorie de maladie Troubles mentaux et du comportement , Autre (BASEC)
  • Study Phase N/A (ICTRP)
  • État du recrutement recrutement en cours (BASEC/ICTRP)
  • Lieu de l’étude
    Zurich
    (BASEC)
  • Responsable de l'étude Caroline Biegel smile@ife.uzh.ch (BASEC)
  • Source(s) de données BASEC: Importé de 24.06.2025 ICTRP: Importé de 12.04.2025
  • Date de mise à jour 24.06.2025 11:36
HumRes63366 | SNCTP000005698 | BASEC2023-01592 | DRKS00033068

SMILE - Difficulties in Learning Mathematics: Intervention Opportunities for Young People

  • Catégorie de maladie Troubles mentaux et du comportement , Autre (BASEC)
  • Study Phase N/A (ICTRP)
  • État du recrutement recrutement en cours (BASEC/ICTRP)
  • Lieu de l’étude
    Zurich
    (BASEC)
  • Responsable de l'étude Caroline Biegel smile@ife.uzh.ch (BASEC)
  • Source(s) de données BASEC: Importé de 24.06.2025 ICTRP: Importé de 12.04.2025
  • Date de mise à jour 24.06.2025 11:36

Résumé de l'étude

A calculation disorder or dyscalculia can be associated with significant limitations for affected individuals: difficulties with large numbers, math anxiety, stress in school, etc. Young people and young adults with a calculation disorder lack support offerings. Therefore, we provide support for them and want to investigate whether and how missing mathematical foundations can be successfully addressed and whether this can change processes in the brain.

(BASEC)

Intervention étudiée

Participants with a calculation disorder/dyscalculia receive individually tailored support (14 sessions of one hour each). They will work together with a professional in individual sessions to address gaps in mathematical understanding. Additionally, they will receive practice materials that they can use at home (on their phone, computer, tablet). To assess the effectiveness of the support, various tests and magnetic resonance imaging (MRI) measurements will be conducted.

(BASEC)

Maladie en cours d'investigation

Dyscalculia/calculation disorder/mathematical learning disorder

(BASEC)

Critères de participation
- Age between 14 and 27 years - Dyscalculia group: dyscalculia diagnosis / control group: no dyscalculia - Normal cognitive development (BASEC)

Critères d'exclusion
- Neurological disorders - Contraindications according to MRI safety criteria (e.g., metal parts in the body, pregnancy, etc.) - Medication that affects neuronal activity (e.g., Ritalin) (BASEC)

Lieu de l’étude

Zurich

(BASEC)

Switzerland (ICTRP)

Sponsor

PD Dr. sc. nat. Karin Kucian

(BASEC)

Contact pour plus d'informations sur l'étude

Personne de contact en Suisse

Caroline Biegel

+41 44 249 77 08

smile@ife.uzh.ch

Universitäts-Kinderspital Zürich Zentrum für MR-Forschung Lenggstrasse 30 CH-8008 Zürich

(BASEC)

Informations générales

Universitts-Kinderspital Zrich - Eleonorenstiftung

+41 44 249 77 08

smile@ife.uzh.ch

(ICTRP)

Informations scientifiques

Universit?ts-Kinderspital Z?rich - Eleonorenstiftung

+41 44 249 77 08

smile@ife.uzh.ch

(ICTRP)

Nom du comité d'éthique approbateur (pour les études multicentriques, uniquement le comité principal)

Commission cantonale de Zurich

(BASEC)

Date d'approbation du comité d'éthique

14.11.2023

(BASEC)


Identifiant de l'essai ICTRP
DRKS00033068 (ICTRP)

Titre officiel (approuvé par le comité d'éthique)
Development and Evaluation of an Intervention for Adolescents and Adults with Dyscalculia (BASEC)

Titre académique
Development and Evaluation of an Intervention for Adolescents and Adults with Dyscalculia - SMILE (ICTRP)

Titre public
Development and Evaluation of an Intervention for Adolescents and Adults with Dyscalculia (ICTRP)

Maladie en cours d'investigation

F81.2Specific disorder of arithmetical skillsF81.2 (ICTRP)

Intervention étudiée
Group 1: Dyscalculics, group 1: receive the support program after a waiting period of 14 to 28 weeks.
- The support program consists of 14 intervention units of one hour as well as exercise material for home over a period of about 14 to 28 weeks
- Participation in four diagnostic appointments: before the waiting period, before the intervention, after the intervention, and 14 to 28 weeks after the intervention
Group 2: Dyscalculics, group 2: receive the support program immediately.
- The support program consists of 14 intervention units of one hour as well as exercise material for home over a period of about 14 to 28 weeks
- Participation in three diagnostic appointments: before the intervention, after the intervention, and 14 to 28 weeks after the intervention
Group 3: Control group without dyscalculia and not participating in the intervention.
- Participation in two diagnostic appointments at intervals of 14 to 28 weeks (ICTRP)

Type d'essai
interventional (ICTRP)

Plan de l'étude
Allocation: Randomized controlled study; Masking: Open (masking not used); Control: No treatment / Standard of care; Assignment: crossover; Study design purpose: treatment (ICTRP)

Critères d'inclusion/exclusion
Inclusion criteria: - Signed informed consent

Dyscalculia group:
- Diagnosis of dyscalculia
- Time and willingness to participate in the intervention (14 sessions 1 hour)
- A score below 73 points in the Basis-Math 4-8 test

Control group:
- No dyscalculia (ICTRP)

Exclusion criteria: - Neurological disorders
- Contraindication according to MR-safety guidelines of the Center for MR-Research of the University Childrens Hospital Zurich
- Pregnancy
- Medication that might have an impact on neuronal activity (e.g. Ritalin)
- Intellectual disability (IQ < 70)

Critères d'évaluation principaux et secondaires
- Improved performance after completing the support program, assessed by means of tests in the field of maths, assessed at all diagnostic appointments as well as at the first and the last intervention unit
- Evaluation of changes in brain activity and structure induced by the support program, assessed by means of magnetic resonance imaging, assessed at all diagnostic appointments (ICTRP)

Evaluation of:
- Neuronal differences between adolescents and adults with dyscalculia and without dyscalculia
- Long term neuronal and behavioural effects of the support program
- Selected learning biography interviews (ICTRP)

Date d'enregistrement
07.12.2023 (ICTRP)

Inclusion du premier participant
24.01.2024 (ICTRP)

Sponsors secondaires
non disponible

Contacts supplémentaires
Caroline Biegel, smile@ife.uzh.ch, +41 44 249 77 08, Universitts-Kinderspital Zrich - Eleonorenstiftung (ICTRP)

ID secondaires
non disponible

Résultats-Données individuelles des participants
Yescoded data might be used for further analyses to answer additional open research questions if participants have given consent. (ICTRP)

Informations complémentaires sur l'essai
http://drks.de/search/en/trial/DRKS00033068 (ICTRP)

Résultats de l'essai

Résumé des résultats

non disponible

Lien vers les résultats dans le registre primaire

non disponible