Informazioni generali
  • Categoria della malattia Chirurgia / intervento / operazione (BASEC)
  • Fase dello studio N/A (ICTRP)
  • Stato di reclutamento reclutamento in corso (BASEC/ICTRP)
  • Luogo dello studio
    Berna
    (BASEC)
  • Responsabile dello studio Patrick Dorn patrick.dorn@insel.ch (BASEC)
  • Fonte dati BASEC: Importato da 06.07.2025 ICTRP: Importato da 12.04.2025
  • Ultimo aggiornamento 06.07.2025 20:31
HumRes61769 | SNCTP000004341 | BASEC2021-00087 | NCT04670523

Removal of thoracic drainage after thoracic surgical minor procedures immediately following the operation

  • Categoria della malattia Chirurgia / intervento / operazione (BASEC)
  • Fase dello studio N/A (ICTRP)
  • Stato di reclutamento reclutamento in corso (BASEC/ICTRP)
  • Luogo dello studio
    Berna
    (BASEC)
  • Responsabile dello studio Patrick Dorn patrick.dorn@insel.ch (BASEC)
  • Fonte dati BASEC: Importato da 06.07.2025 ICTRP: Importato da 12.04.2025
  • Ultimo aggiornamento 06.07.2025 20:31

Descrizione riassuntiva dello studio

The management of thoracic drainage after thoracic procedures is a key element of postoperative care. Over the last decade, minimally invasive techniques and standardized treatment pathways (keyword 'ERAS' (enhanced recovery after surgery)) have significantly altered the recovery phase after lung procedures, leading to a reduction in postoperative complications and an increase in quality of life. Thoracic drainage remains a significant issue as it contributes to postoperative pain and worsens lung function. Therefore, there is increased interest in earlier removal of thoracic drains, not only for economic reasons but also for improved quality of life and potential reduction of postoperative complications. Meanwhile, improved drainage systems have been developed that allow for more precise quantification and contribute to increased decision-making certainty regarding drainage removal. Nevertheless, drainage remains in current practice until at least the first day after surgery, even in the absence of indications of incomplete lung or chest wall healing (absence of air leakage or increased or bloody fluid secretion) and limits the patient's mobility and well-being during this time. In this study, we investigate the safety of removing thoracic drainage immediately after surgery in the absence of reasons for inadequate lung or tissue healing (no air leakage and no increased or bloody drainage quality) based on a protocol with the electronic drainage system.

(BASEC)

Intervento studiato

Removal of thoracic drainage after thoracic surgical minor procedures such as extra-anatomical lung resections and biopsies of the pleura immediately following the operation

(BASEC)

Malattie studiate

For complete re-expansion of the lung and for drainage of excessive fluid, after minimally invasive (thoracoscopy) and open lung procedures, as well as other procedures in the thoracic cavity, one or more thoracic drains ('chest drain') are inserted before closing the wounds. The removal of these drains has so far been decided in the further course after surgery according to, for example, the air-tightness of the lung and the amount of drained fluid.

(BASEC)

Criteri di partecipazione
1. Non-anatomical lung resection (also 'lung biopsy') in camera technique (thoracoscopy) 2. Biopsy of the pleura in camera technique (thoracoscopy) 3. Signed consent 4. Legal age (BASEC)

Criteri di esclusione
1. Anatomical lung resections 2. Pleural empyema (= inflammation / pus between the lung and chest wall) 3. Surgical treatment and evaluation of fluid in the space between the lung and chest wall 4. Pleurodesis (= chemical adhesion of lung to chest wall) in camera technique 5. Vulnerable persons pregnancy, not reached legal age (BASEC)

Luogo dello studio

Berna

(BASEC)

Switzerland (ICTRP)

Sponsor

non disponibile

Contatto per ulteriori informazioni sullo studio

Persona di contatto in Svizzera

Patrick Dorn

031 632 37 45

patrick.dorn@insel.ch

(BASEC)

Informazioni generali

Chief, Department of General Thoracic Surgery, Inselspital

0041 31 632 37 45;0041 31 632 37 45;

patrick.dorn@insel.ch

(ICTRP)

Informazioni generali

Chief, Department of General Thoracic Surgery, Inselspital

0041 31 632 37 450041 31 632 37 45

patrick.dorn@insel.ch

(ICTRP)

Informazioni scientifiche

Chief, Department of General Thoracic Surgery, Inselspital

0041 31 632 37 45;0041 31 632 37 45;

patrick.dorn@insel.ch

(ICTRP)

Nome del comitato etico approvante (per studi multicentrici solo il comitato principale)

Commissione d'etica Berna

(BASEC)

Data di approvazione del comitato etico

01.04.2021

(BASEC)


ID di studio ICTRP
NCT04670523 (ICTRP)

Titolo ufficiale (approvato dal comitato etico)
non disponibile

Titolo accademico
Early Postoperative Day 0 Chest Tube Removal After Thoracoscopic Minor Surgeries. A Randomized Controlled Clinical Trial. (ICTRP)

Titolo pubblico
Early Postoperative Day 0 Chest Tube Removal After Thoracoscopic Minor Surgeries (ICTRP)

Malattie studiate
Lung Pathologies of Unclear Etiology (ICTRP)

Intervento studiato
Procedure: Early postoperative day 0 (POD 0) chest tube removal.Procedure: Chest tube removal according to traditional standard protocol not earlier than on postoperative day 1 (POD 1). (ICTRP)

Tipo di studio
Interventional (ICTRP)

Disegno dello studio
Allocation: Randomized. Intervention model: Parallel Assignment. Primary purpose: Treatment. Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor). (ICTRP)

Criteri di inclusione/esclusione
Inclusion Criteria:

1. Thoracoscopic extra-anatomical lung resection (surgical lung biopsy)

2. Thoracoscopic pleural biopsy

3. Signed consent

4. Age of majority

Exclusion Criteria:

1. Anatomical resection

2. Empyema

3. Pleural effusion

4. Pleurodesis

5. Vulnerable persons (Pregnant women, Children and adolescents) (ICTRP)

non disponibile

Endpoint primari e secondari
1. Pneumothorax requiring chest tube reinsertion;2. Pleural effusion requiring thoracocentesis;3. Prolonged air leak > 5 days;4. Re-admission or reoperation due to pleural complication (ICTRP)

1. Cardiopulmonary complications (Pneumonia, Atrial fibrillation, ARDS);2. Re-operation;3. Length of drainage (days);4. Length of stay (days) (ICTRP)

Data di registrazione
27.11.2020 (ICTRP)

Inclusione del primo partecipante
non disponibile

Sponsor secondari
non disponibile

Contatti aggiuntivi
Patrick Dorn, PD;Patrick Dorn, PD;Patrick Dorn, PD, patrick.dorn@insel.ch, 0041 31 632 37 45;0041 31 632 37 45;, Chief, Department of General Thoracic Surgery, Inselspital (ICTRP)

ID secondari
EROCT (ICTRP)

Risultati-Dati individuali dei partecipanti
non disponibile

Ulteriori informazioni sullo studio
https://clinicaltrials.gov/ct2/show/NCT04670523 (ICTRP)

Risultati dello studio

Riepilogo dei risultati

non disponibile

Link ai risultati nel registro primario

non disponibile