Informations générales
  • Catégorie de maladie Maladies ostéomusculaires (BASEC)
  • État du recrutement recrutement pas encore commencé (BASEC/ICTRP)
  • Lieu de l’étude
    Berne, Zurich
    (BASEC)
  • Responsable de l'étude William R. Taylor bt@ethz.ch (BASEC)
  • Source(s) de données BASEC: Importé de 11.11.2025 ICTRP: N/A
  • Date de mise à jour 11.11.2025 09:30
HumRes67401 | SNCTP000006636 | BASEC2025-01195

Impact of Shoe Sole Shape on Knee Movement in Individuals with Knee Osteoarthritis

  • Catégorie de maladie Maladies ostéomusculaires (BASEC)
  • État du recrutement recrutement pas encore commencé (BASEC/ICTRP)
  • Lieu de l’étude
    Berne, Zurich
    (BASEC)
  • Responsable de l'étude William R. Taylor bt@ethz.ch (BASEC)
  • Source(s) de données BASEC: Importé de 11.11.2025 ICTRP: N/A
  • Date de mise à jour 11.11.2025 09:30

Résumé de l'étude

Osteoarthritis in the knee often arises from repeated or excessive strain in daily activities, such as walking or climbing stairs. This gradually degrades the cartilage in the knee joint, leading to severe pain. It is estimated that more than half of individuals with symptomatic knee osteoarthritis will eventually require a knee replacement. This not only poses a significant burden on those affected but also costs the healthcare system a lot of money. Knee osteoarthritis is particularly common in individuals whose legs are in a bow-legged position. This typically places significant stress on only one side of the knee. It has been shown that special shoes and insoles can alter the strain while walking and thus alleviate pain. However, their effectiveness is limited, and they are often uncomfortable. Therefore, they do not significantly slow the progression of the disease. In our study, we aim to test the effect of a shoe prototype currently in development. The shoe features a modified sole shape and stiffness, which could positively influence walking and knee strain. To determine how these shoes affect knee movement, we utilize a specialized X-ray system at ETH Zurich. The device moves along a rail and follows the test subject while simultaneously capturing X-ray images of the affected knee.

(BASEC)

Intervention étudiée

The shoe is a prototype. The shoe soles are manufactured using 3D printing technology by swissbiomechanics AG and are characterized by a special sole shape. Both the material properties and the geometric features of the sole are designed to specifically support the potential benefits of foot eversion.

At the Institute of Biomechanics at ETH Zurich, a gait analysis will be conducted using the shoe prototype, a neutral shoe, and a neutral shoe with a laterally elevated insole. This allows for the examination of gait patterns, foot positioning, and the alignment of the lower limbs.

(BASEC)

Maladie en cours d'investigation

Knee Osteoarthritis Knee osteoarthritis is a chronic, progressive condition characterized by the degradation of cartilage in the knee joint. This leads to pain, reduced mobility, and in many cases, the necessity for a knee replacement in advanced stages.

(BASEC)

Critères de participation
• Clinical criteria of the American College of Rheumatology (ACR) for knee osteoarthritis (OA); • Radiologically confirmed symptomatic knee osteoarthritis for at least 6 months; • Radiological criteria: X-rays showing tibiofemoral knee osteoarthritis, defined as at least Kellgren and Lawrence grade 2 (radiographic evidence of at least one osteophyte in the tibiofemoral joint) (BASEC)

Critères d'exclusion
• Women who are pregnant or breastfeeding; • Inability to follow the study procedures; • Non-knee-related musculoskeletal pain that is equal to or greater than knee pain (BASEC)

Lieu de l’étude

Berne, Zurich

(BASEC)

non disponible

Sponsor

William R. Taylor

(BASEC)

Contact pour plus d'informations sur l'étude

Personne de contact en Suisse

William R. Taylor

+41 44 633 05 95

bt@ethz.ch

ETH Zürich

(BASEC)

Informations scientifiques

non disponible

Nom du comité d'éthique approbateur (pour les études multicentriques, uniquement le comité principal)

Commission cantonale de Zurich

(BASEC)

Date d'approbation du comité d'éthique

17.10.2025

(BASEC)


Identifiant de l'essai ICTRP
non disponible

Titre officiel (approuvé par le comité d'éthique)
Effect of Shoe Sole Design on Tibiofemoral Kinematics in People with Knee Osteoarthritis: A Dynamic Dual-plane Fluoroscopy Study (BASEC)

Titre académique
non disponible

Titre public
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Maladie en cours d'investigation
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Intervention étudiée
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Type d'essai
non disponible

Plan de l'étude
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Critères d'inclusion/exclusion
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non disponible

Critères d'évaluation principaux et secondaires
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Date d'enregistrement
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Inclusion du premier participant
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Sponsors secondaires
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Contacts supplémentaires
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ID secondaires
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Résultats-Données individuelles des participants
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Informations complémentaires sur l'essai
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Résultats de l'essai

Résumé des résultats

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Lien vers les résultats dans le registre primaire

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