Evaluation of a combination therapy with psychological short therapy and antidepressants for the treatment of depression in Zimbabwe.
Résumé de l'étude
Mental illnesses such as depression are increasing even in resource-poor countries. It is the most common mental illness in Africa. Although one in four patients in primary care suffers from depression, up to 90% of them remain untreated. This is partly due to the lack of specialists. The research project collaborates with the 'Friendship Bench.' This locally developed program in Zimbabwe aims to close this gap in care. To improve treatment outcomes for depression, we want to combine the psychological short intervention of the 'Friendship Bench' with antidepressants. These will be administered by trained health personnel without specialization in psychiatry. Our clinical study compares the psychological short intervention of the 'Friendship Bench' with the 'Friendship Bench' plus antidepressants and examines how many individuals still suffer from depression after four months. Our research follows international treatment guidelines. Zimbabwe is one of the WHO target countries under its special initiative to improve access to mental health care. Accordingly, our project is conducted in close collaboration with the Ministry of Health of Zimbabwe and the WHO. This ensures that our results achieve the necessary long-term impact.
(BASEC)
Intervention étudiée
We are investigating the 'Friendship Bench Plus Intervention.' This is a psychological short intervention provided by lay therapists consisting of six psychotherapy sessions plus antidepressants prescribed by nursing professionals.
(BASEC)
Maladie en cours d'investigation
Moderate to severe depression.
(BASEC)
We include adults (≥18 years) with moderate to severe depression who are seeking treatment at a health center in Harare and have not yet been treated for their depression. (BASEC)
Critères d'exclusion
Individuals with severe physical comorbidities, with psychotic symptoms or high suicide risk, as well as pregnant women will be excluded. (BASEC)
Lieu de l’étude
Berne, Autre
(BASEC)
Harare, Simbabwe
(BASEC)
Sponsor
Universität Bern
(BASEC)
Contact pour plus d'informations sur l'étude
Personne de contact en Suisse
Prof Monika Müller, MD PhD
+41 31 930 91 11
monika_mueller@cluttergmx.chUniversitätsklinik für Psychiatrie und Psychotherapie der UPD Bern (Gastdozentin, Korrespondenz bitte an Privatadresse Monika Müller, Stürlerstrasse 5, 3006 Bern)
(BASEC)
Informations scientifiques
non disponible
Nom du comité d'éthique approbateur (pour les études multicentriques, uniquement le comité principal)
Commission cantonale d'éthique de Berne
(BASEC)
Date d'approbation du comité d'éthique
19.03.2025
(BASEC)
Identifiant de l'essai ICTRP
non disponible
Titre officiel (approuvé par le comité d'éthique)
Combining antidepressants with psychological therapy to improve depression outcome in Zimba-bwe - the Friendship Bench Plus trial (FB+Trial) (BASEC)
Titre académique
non disponible
Titre public
non disponible
Maladie en cours d'investigation
non disponible
Intervention étudiée
non disponible
Type d'essai
non disponible
Plan de l'étude
non disponible
Critères d'inclusion/exclusion
non disponible
non disponible
Critères d'évaluation principaux et secondaires
non disponible
non disponible
Date d'enregistrement
non disponible
Inclusion du premier participant
non disponible
Sponsors secondaires
non disponible
Contacts supplémentaires
non disponible
ID secondaires
non disponible
Résultats-Données individuelles des participants
non disponible
Informations complémentaires sur l'essai
non disponible
Résultats de l'essai
Résumé des résultats
non disponible
Lien vers les résultats dans le registre primaire
non disponible