What effects does radiofrequency have in liver surgeries? Can it help prevent cancer recurrence?

Zusammenfassung der Studie

Liver cancer is the sixth most common cancer worldwide and the third leading cause of cancer-related death. Furthermore, the liver is also the primary site for metastases from colorectal cancer, which is the third most common malignant disease worldwide. The standard treatment for liver cancer and liver metastases from colorectal cancer is the surgical removal of the tumor-bearing part of the liver. However, after such surgeries, cancer often recurs. Further research is needed to find a solution to this problem. It may help to treat the tumor margins after surgery with a radiofrequency device to reduce the number of tumor recurrences. This method applies high-frequency electromagnetic waves to the tissue at the tumor margins. The device heats the tissue and thereby kills cancer cells that may have remained after surgery. In the study, participants are randomly assigned to two groups. In the experimental group, liver cell cancer or liver metastases are surgically removed and the tumor margins are additionally cauterized using radiofrequency. In the control group, the cancer is only surgically removed. No additional treatment of the tumor margins is performed. Only the study staff will know which group the participants were assigned to. The aim of the study is to determine whether the additional cauterization of the tumor margins with a radiofrequency device can reduce the local recurrence rate of this cancer.

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Untersuchte Intervention

Surgical removal of liver cell cancer or liver metastases from colon cancer. In the experimental group, the tumor margins are also cauterized using radiofrequency, while in the control group no further treatment of the tumor margins is performed.

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Untersuchte Krankheit(en)

Liver cell cancer or liver metastases caused by colon or rectal cancer

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Sponsor

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