Allgemeine Informationen
  • Krankheitskategorie Grundlagenforschung (Anatomie/Physiologie) , Andere (BASEC)
  • Studienphase N/A (ICTRP)
  • Rekrutierungsstatus Rekrutierung läuft (BASEC/ICTRP)
  • Studienstandort
    Zürich
    (BASEC)
  • Studienverantwortliche PD Dr Michael L. Meier michael.meier@balgrist.ch (BASEC)
  • Datenquelle(n) BASEC: Import vom 29.04.2025 ICTRP: Import vom 19.04.2023
  • Letzte Aktualisierung 29.04.2025 13:51
HumRes55407 | SNCTP000004608 | BASEC2021-01331 | NCT04869514

The influence of spinal manipulation on lumbar proprioception

  • Krankheitskategorie Grundlagenforschung (Anatomie/Physiologie) , Andere (BASEC)
  • Studienphase N/A (ICTRP)
  • Rekrutierungsstatus Rekrutierung läuft (BASEC/ICTRP)
  • Studienstandort
    Zürich
    (BASEC)
  • Studienverantwortliche PD Dr Michael L. Meier michael.meier@balgrist.ch (BASEC)
  • Datenquelle(n) BASEC: Import vom 29.04.2025 ICTRP: Import vom 19.04.2023
  • Letzte Aktualisierung 29.04.2025 13:51

Zusammenfassung der Studie

Back pain represents a major health economic problem worldwide. In cases of acute back pain, symptoms usually improve spontaneously, but in 10-15% of cases, the problem becomes chronic. Pain is often localized in the lumbar region and buttocks, and in most cases (up to 85%), no precise diagnosis can be made. Spinal manipulation, a technique of manual medicine, often leads to an improvement in pain symptoms. It is assumed that biomechanical as well as neurophysiological processes are associated with the observed pain relief. However, the underlying mechanisms are still largely unknown, necessitating further research to ultimately better understand and more effectively utilize spinal manipulation. There is evidence that spinal manipulation may have a positive effect on proprioception (the perception of the body in space, the position and movement of the trunk and limbs) (in patients with back pain, this is often impaired). By stimulating the proprioceptive system, spinal manipulation could stimulate the perception and processing of sensory signals, which could generally optimize the sensorimotor function (the interplay of the sensory and motor systems) of the spine and thus lead to pain relief and finer movement patterns.

(BASEC)

Untersuchte Intervention

spinal manipulation

(BASEC)

Untersuchte Krankheit(en)

chronic back pain

(BASEC)

Kriterien zur Teilnahme
- Age between 18 and 50 years. - No disorders that could affect gait or normal standing. (BASEC)

Ausschlusskriterien
- No chiropractic treatment (or similar manual technique) in the last 2 weeks - Overweight or underweight (16 < Body Mass Index > 30). - Long-term use of corticosteroid medications. (BASEC)

Studienstandort

Zürich

(BASEC)

nicht verfügbar

Sponsor

-

(BASEC)

Kontakt für weitere Auskünfte zur Studie

Kontaktperson Schweiz

PD Dr Michael L. Meier

+41 44 510 73 80

michael.meier@balgrist.ch

Balgrist University Hospital

(BASEC)

Allgemeine Auskünfte

0445107382

michael.meier@balgrist.ch

(ICTRP)

Name der bewilligenden Ethikkommission (bei multizentrischen Studien nur die Leitkommission)

Ethikkommission Zürich

(BASEC)

Datum der Bewilligung durch die Ethikkommission

07.09.2021

(BASEC)


ICTRP Studien-ID
NCT04869514 (ICTRP)

Offizieller Titel (Genehmigt von der Ethikkommission)
Does spinal manipulation therapy impact lumbar proprioception? (BASEC)

Wissenschaftlicher Titel
Does Spinal Manipulation Therapy Impact Lumbar Proprioception? A Double-blind Randomized Controlled Trial Examining the Influence of Spinal Manipulative Therapy (SMT) Versus a Sham and Non-sham Control Intervention on Proprioceptive Function (ICTRP)

Öffentlicher Titel
Does Spinal Manipulation Therapy Impact Lumbar Proprioception (ICTRP)

Untersuchte Krankheit(en)
Manipulation, Psychologic
Proprioception
Vibration; Exposure
(ICTRP)

Untersuchte Intervention
Procedure: spinal manipulation
(ICTRP)

Studientyp
Interventional (ICTRP)

Studiendesign
Allocation: Randomized. Intervention model: Parallel Assignment. Primary purpose: Basic Science. Masking: Triple (Participant, Care Provider, Outcomes Assessor). (ICTRP)

Ein-/Ausschlusskriterien
Inclusion Criteria: - Aged between 18 and 50 - No chiropractic intervention (or similar) in the last 3 months - No episode of musculoskeletal pain in the past 3 months - No history of chronic pain (longer than 3 months) - No history of vestibular disorders Exclusion Criteria: - Excessive consumption of alcohol or consumption of other drugs or analgesics within the last 24 h - Pregnancy - Prior foot/ankle or spine surgery - Any neuromuscular diseases that might affect gait and posture and injuries of the motor system with permanent deformities - Body mass index (BMI) > 30 kg/m2
Minimum age: 18 Years
Maximum age: 50 Years
Sex: All (ICTRP)

nicht verfügbar

Primäre und sekundäre Endpunkte
Postural sway (mm)
Proprioceptive weighting ratio (value between 0 and 1)
(ICTRP)

Belief score influence of manipulation on balance control
Tampa-Scale for Kinesiophobia for the general population (TSK-G) questionnaire score
(ICTRP)

Registrierungsdatum
28.04.2021 (ICTRP)

Einschluss des ersten Teilnehmers
01.09.2021 (ICTRP)

Sekundäre Sponsoren
nicht verfügbar

Weitere Kontakte
Michael L Meier, PhD, michael.meier@balgrist.ch, 0445107382 (ICTRP)

Sekundäre IDs
Project Nexus (ICTRP)

Angaben zur Verfügbarkeit von individuellen Teilnehmerdaten
nicht verfügbar

Weitere Informationen zur Studie
http://www.who.int/trialsearch/Trial2.aspx?TrialID=NCT04869514 (ICTRP)


Ergebnisse der Studie

Zusammenfassung der Ergebnisse

nicht verfügbar

Link zu den Ergebnissen im Primärregister

nicht verfügbar