Multimodal (multistage) prehabilitation for major surgical procedures in older patients to reduce complication rates and costs: A randomized, prospective, monocentric, multidisciplinary study (PREHABIL study).

Zusammenfassung der Studie

Participants will be randomly assigned to one of two groups. In the first group, the control group, preparation is done according to the usual method in the treating clinic (orthopedics, urology, abdominal surgery, etc.). In the second group, the intervention group, a multistage preparation is conducted. This consists of an individually tailored package of physical exercise under physiotherapeutic guidance, preventive treatment of any potential anemia, correction of malnutrition, and support for smoking cessation. With your consent, the treating surgeon will refer you to us. First, a series of examinations (strength and endurance tests, blood analyses) will be conducted, as well as some questionnaires to be filled out. If you are assigned to the intervention group, we will then begin the aforementioned preparations over a period of two to four weeks. If you belong to the control group, this step will be omitted. The day before the surgery, this examination will be repeated to assess the effect of the interventions. Four weeks after the surgery, you will receive questionnaires from us again. Your time commitment may vary significantly depending on group assignment. For the control group, we estimate a commitment of about 8 hours, spread over 3 to 4 hospital visits. For the intervention group, at least two additional hospital visits for training guidance of one hour each, along with the time commitment for home training (5x30min/week) and possibly consultations in the clinic for nutritional counseling (30min each) will be added. We try to minimize your commitment by combining visits to the various clinics (operating clinic, anesthesia, physiotherapy, nutritional counseling) whenever possible.

(BASEC)

Untersuchte Intervention

Multimodal pre-habilitation: physical activity, anemia (low blood count) correction, diet optimization and smoking cessation.

(BASEC)

Untersuchte Krankheit(en)

The study examines whether it is possible to positively influence recovery after surgery with multimodal (multi-stage) preparation of the patient. We hope to prevent possible complications and ultimately reduce the follow-up costs of the intervention.

(BASEC)

Sponsor

not applicable

(BASEC)

Name der bewilligenden Ethikkommission (bei multizentrischen Studien nur die Leitkommission)

Ethikkommission Bern

(BASEC)

Datum der Bewilligung durch die Ethikkommission

13.07.2021

(BASEC)

Ergebnisse der Studie