GASTRIC-PICU: Study on the usefulness of measuring gastric residual volume in children in intensive care
Summary description of the study
In our research project, we want to find out whether routine measurements of gastric contents in children are necessary or not. Children in intensive care and on mechanical ventilation often struggle to take in even half of the required calories (through food). An adequate caloric intake for a sick child is important so that he/she has enough energy for breathing and recovery. Currently, the gastric residual volume is regularly measured in every child. As soon as this gastric residual shows an abnormal amount or color, the staff may, after consultation, reduce or stop feeding. This could be a reason why these children do not receive sufficient calories.
(BASEC)
Intervention under investigation
When participating in the study, the child will be randomly assigned to one of two groups:
• No measurement of gastric residual volume (GRV) (intervention group)
• Standard measurement of GRV (comparison group)
The rest of the child's treatment will not be influenced by the study. Care continues according to the therapeutic guidelines of the treating medical and nursing team.
(BASEC)
Disease under investigation
We want to know if measuring gastric residual volume affects ventilation and if caloric intake can be increased.
(BASEC)
Children and adolescents who can be included in this study must meet the following criteria: o Patient in intensive care o Already mechanically ventilated or expected intubation o Age 0-16 years o Intention to start or already started feeding via gastric tube or PEG. (BASEC)
Exclusion criteria
Children and adolescents cannot participate in this study if the following applies to them: • Already a patient in intensive care for more than 24 hours • Postpyloric feeding tubes or jejunostomy • Palliative patients • Children/adolescents with long-term invasive mechanical ventilation • Current or recently occurred intestinal disease or surgery (e.g., necrotizing enterocolitis (NEC), active gastrointestinal bleeding, or intestinal surgery) • Participated in the GASTRIC-PICU study in the last six months. (BASEC)
Trial sites
Zurich
(BASEC)
Sponsor
Universitäts-Kinderspital Zürich
(BASEC)
Contact
Contact Person Switzerland
Luregn Schlapbach
+41 44 249 6211
research.ipsneo@clutterkispi.uzh.chUniversitäts-Kinderspital Zürich, Intensivmedizin und Neonatologie
(BASEC)
Scientific Information
not available
Name of the authorising ethics committee (for multicentre studies, only the lead committee)
Ethics Committee Zurich
(BASEC)
Date of authorisation
10.12.2024
(BASEC)
ICTRP Trial ID
not available
Official title (approved by ethics committee)
The GASTRIC-PICU Study: A randomised controlled trial of no routine gastric residual monitoring to guide enteral feeding in paediatric intensive care units (BASEC)
Academic title
not available
Public title
not available
Disease under investigation
not available
Intervention under investigation
not available
Type of trial
not available
Trial design
not available
Inclusion/Exclusion criteria
not available
not available
Primary and secondary end points
not available
not available
Registration date
not available
Incorporation of the first participant
not available
Secondary sponsors
not available
Additional contacts
not available
Secondary trial IDs
not available
Results-Individual Participant Data (IPD)
not available
Further information on the trial
not available
Results of the trial
Results summary
not available
Link to the results in the primary register
not available