Improving Cervical Cancer Screening Coverage Among Unscreened Women Aged 50 to 74 in Switzerland Through HPV Self-Collection Strategies: A Randomized Study
Summary description of the study
The BRAICS project aims to improve cervical cancer screening coverage in Switzerland. It plans to invite underserved women participating in organized breast cancer screening programs to take part in cervical cancer screening. The goal of the project is to reduce inequalities in access to screening while supporting health policy decision-making.
(BASEC)
Intervention under investigation
Intervention Group 1 (IG1) - Awareness of Cervical Cancer Screening. Women in the IG1 group will receive an awareness letter encouraging them to undergo cervical cancer screening and to make an appointment at a medical center of their choice. The letter, sent by post or email, will highlight Swiss recommendations and the importance of regular screening for early detection.
Intervention Group 2 (IG2) - HPV Self-Test at Home. Women in the IG2 group will receive a free kit for vaginal self-collection of HPV infections with a prepaid envelope for returning the sample. The samples will be analyzed for high-risk HPV types using PCR. Results will be communicated via email or post, and positive women will be contacted for thorough gynecological follow-up, which includes a Pap test and possibly further examinations.
(BASEC)
Disease under investigation
Cervical Cancer
(BASEC)
- Women who have received invitation letters from the BCS in the five selected cantons (Geneva, Bern (French-speaking), Jura, Neuchâtel, and Vaud) - Aged 50 to 74 years - Not screened for cervical cancer in the last three years - Speak one of the 6 languages of the study (French, German, Italian, and English, Spanish, and Portuguese) (BASEC)
Exclusion criteria
- Previous cervical cancer diagnosis, - Hysterectomy - No consent to participate in the study - Incapable of judgment or under guardianship - Pregnancy (BASEC)
Trial sites
Geneva
(BASEC)
Sponsor
Haute Ecole de Santé Genève
(BASEC)
Contact
Contact Person Switzerland
Jessica Di Vincenzo-Sormani
+41 22 558 58 78
braics.heds@clutterhesge.chHaute Ecole de Santé de Genève
(BASEC)
Scientific Information
not available
Name of the authorising ethics committee (for multicentre studies, only the lead committee)
Ethics Committee Geneva
(BASEC)
Date of authorisation
31.07.2025
(BASEC)
ICTRP Trial ID
not available
Official title (approved by ethics committee)
Improving cervical cancer screening coverage among underscreened women aged 50 to 74 in Switzerland using HPV self-sampling strategies: A Randomized Study (BASEC)
Academic title
not available
Public title
not available
Disease under investigation
not available
Intervention under investigation
not available
Type of trial
not available
Trial design
not available
Inclusion/Exclusion criteria
not available
not available
Primary and secondary end points
not available
not available
Registration date
not available
Incorporation of the first participant
not available
Secondary sponsors
not available
Additional contacts
not available
Secondary trial IDs
not available
Results-Individual Participant Data (IPD)
not available
Further information on the trial
not available
Results of the trial
Results summary
not available
Link to the results in the primary register
not available