Daily Consumption of Teff Injera and Its Effect on Gut Microbiome and Well-Being
Summary description of the study
In this study, we want to find out whether the daily consumption of teff injera affects the balance of gut bacteria and overall well-being. The study lasts a total of 4 weeks. During this time, you will come to us 4 times. At the appointments, you will provide blood and stool samples and answer short questionnaires about diet and well-being. The total time commitment is about 2–3 hours over the entire study duration. You will be assigned to one of two groups. • In the injera group, you will eat teff injera every day for two weeks. • In the comparison group, you will not change your diet. During the study, minor discomforts may occur, such as bloating, softer stools, or a small bruise after a blood draw. Rarely, an allergic reaction to teff may also occur. If you have a known intolerance or allergy, you cannot participate. There is no direct benefit for you personally. However, your participation helps us better understand how diet can affect gut health. Participation is voluntary. You can stop at any time without giving reasons.
(BASEC)
Intervention under investigation
This study investigates the daily consumption of teff injera. Teff injera is a traditional flatbread made from the grain teff. Participants in the intervention group will eat teff injera daily for 2 weeks. The goal is to examine whether this dietary pattern affects the balance of gut bacteria as well as overall well-being.
(BASEC)
Disease under investigation
Influence of a Traditional Food on Healthy Participants
(BASEC)
You can participate in this study if you: • are between 18 and 65 years old, • are generally healthy (no chronic metabolic or inflammatory disease), • are willing to eat teff injera daily for 14 days (intervention group), • are willing to provide stool and blood samples and fill out questionnaires over 4 weeks, • have read, understood, and provided written consent to the patient information. (BASEC)
Exclusion criteria
Individuals excluded from participation (exclusion criteria) are: • those with a known allergy or intolerance to teff, • those who are pregnant or breastfeeding, • those who have taken antibiotics or probiotic supplements in the last 3 months, • those who are on a strict gluten-free diet or another strict exclusion diet, • those with diagnosed chronic diseases of the digestive tract, metabolism, or immune system (e.g., chronic inflammatory bowel disease, autoimmune disease, diabetes mellitus), • those who have participated in another clinical intervention study within the last 30 days, • those who are unable to comply with the study requirements for health or personal reasons. (BASEC)
Trial sites
Zurich
(BASEC)
Sponsor
Anne Müller Universität Zürich, IMCR
(BASEC)
Contact
Contact Person Switzerland
Lydia Kirsche
044 635 34 77
kirsche@clutterimcr.uzh.chUniversität Zürich
(BASEC)
Scientific Information
not available
Name of the authorising ethics committee (for multicentre studies, only the lead committee)
Ethics Committee Zurich
(BASEC)
Date of authorisation
24.10.2025
(BASEC)
ICTRP Trial ID
not available
Official title (approved by ethics committee)
Teff consumption as a modulator of microbiota composition and diversity (BASEC)
Academic title
not available
Public title
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Disease under investigation
not available
Intervention under investigation
not available
Type of trial
not available
Trial design
not available
Inclusion/Exclusion criteria
not available
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Primary and secondary end points
not available
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Registration date
not available
Incorporation of the first participant
not available
Secondary sponsors
not available
Additional contacts
not available
Secondary trial IDs
not available
Results-Individual Participant Data (IPD)
not available
Further information on the trial
not available
Results of the trial
Results summary
not available
Link to the results in the primary register
not available