Effects of LSD on Neuroplasticity in Healthy Individuals
Summary description of the study
We want to investigate in this study whether treatment with LSD increases the neuroplasticity of the brain. Neuroplasticity is the brain's ability to form new connections and reorganize in response to new events. The results could be very important for the clinical development of new treatments for mental disorders. All healthy individuals can participate in the study if they meet the inclusion and exclusion criteria. Participation in the study involves a total of 8 laboratory visits, spread over at least 6 weeks. On two different dates, you will receive a dose of LSD ranging from 0 to 0.1 mg (100 micrograms). It will be randomly determined which dose you receive on which date. Neither you nor the study staff will know when you receive which dose (the study will therefore be conducted as
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Intervention under investigation
As part of the study, you will take LSD in an alcoholic liquid on two different days, between 0 and 0.1 mg (100 micrograms). There will be at least a one-month interval between these two dates.
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Disease under investigation
Healthy Participants
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Physically and mentally healthy Aged between 21 and 55 years Right-handed (BASEC)
Exclusion criteria
Excessive substance use (including nicotine, alcohol, drugs, and medications) Personal or family history of psychotic disorders Arterial hypertension (BASEC)
Trial sites
Freiburg
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Sponsor
Prof. Gregor Hasler
(BASEC)
Contact
Contact Person Switzerland
Abigail Calder
+41 26 304 26 05
abigail.calder@clutterunifr.chUniversity of Fribourg
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Scientific Information
not available
Name of the authorising ethics committee (for multicentre studies, only the lead committee)
Ethics Committee Bern
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Date of authorisation
08.11.2021
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ICTRP Trial ID
not available
Official title (approved by ethics committee)
Effects of Lysergic Acid Diethylamide (LSD) on Neuroplasticity in Healthy Human Subjects (BASEC)
Academic title
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Public title
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Disease under investigation
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Intervention under investigation
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Type of trial
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Trial design
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Inclusion/Exclusion criteria
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Primary and secondary end points
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Registration date
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Incorporation of the first participant
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Secondary sponsors
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Additional contacts
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Secondary trial IDs
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Results-Individual Participant Data (IPD)
not available
Further information on the trial
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Results of the trial
Results summary
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Link to the results in the primary register
not available